Particle Therapy for Cancer and Noncancer Diseases
نویسنده
چکیده
*email: [email protected] High-energy charged particles are considered today the most advanced, cutting-edge technology in radiotherapy. The physical advantages (Bragg peak) combined with the special biological properties of densely ionizing radiation makes them the elective choice for tumors close to organs at risk, and a potential breakthrough for different cancer and noncancer diseases with high incidence and mortality. The main hindrance to a widespread use of ions in therapy is the high cost/benefit ratio. Compact, cheaper accelerators and the extension of the diseases eligible for particle therapy treatments are necessary to decrease this ratio.
منابع مشابه
Particle therapy for noncancer diseases.
Radiation therapy using high-energy charged particles is generally acknowledged as a powerful new technique in cancer treatment. However, particle therapy in oncology is still controversial, specifically because it is unclear whether the putative clinical advantages justify the high additional costs. However, particle therapy can find important applications in the management of noncancer diseas...
متن کاملStudies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997.
This continues the series of general reports on mortality in the cohort of atomic bomb survivors followed up by the Radiation Effects Research Foundation. This cohort includes 86,572 people with individual dose estimates, 60% of whom have doses of at least 5 mSv. We consider mortality for solid cancer and for noncancer diseases with 7 additional years of follow-up. There have been 9,335 deaths ...
متن کاملEarly life exposure to the 1918 influenza pandemic and old-age mortality by cause of death.
OBJECTIVES We sought to analyze how early exposure to the 1918 influenza pandemic is associated with old-age mortality by cause of death. METHODS We analyzed the National Health Interview Survey (n = 81,571; follow-up 1989-2006; 43,808 deaths) and used year and quarter of birth to assess timing of pandemic exposure. We used Cox proportional and Fine-Gray competing hazard models for all-cause ...
متن کاملThe biological effects induced by high-charged and energy particles and its application in cancer therapy
The radiobiological effects of high atomic number and energy (HZE particles) ion beams are of interest for radioprotection in space and tumor radiotherapy. Space radiation mainly consists of heavy charged particles from protons to iron ions, which is distinct from common terrestrial forms of radiation. HZE particles pose a significant cancer risk to astronauts on prolonged space missions. With ...
متن کاملMonte Carlo calculations of dose distribution for the treatment of gastric cancer with proton therapy
Proton therapy is a common form of external radiation therapy based on the manipulation of Bragg peak of this beam, it can treat the tumor by delivering high levels of doses to it, while protecting surrounding healthy tissues against radiation. In this work, the dose distribution of proton and secondary particles such as neutrons, photons, electrons and positrons in gastric cancer proton therap...
متن کامل